C

chromatin

A visualization software for 3D chromatin chain 🧬 by University of Applied Sciences Stralsund.

Live Demo                  Live Demo (BETA)

Insight into the 3D organization of the genome, this question arises: Are the genes for the corresponding protein complexes, whose transcription needs to be orchestrated, located in the same 3D-chromatin domain? Using human protein complex database and high-resolution Hi-C data on normal and cancer human cells, I elaborated an R-based approach to normalize the data and statistically test the association to TAD (topologically associating domain) in my bioinformatics master's work.

New package repo & site: https://github.com/Pasquali-lab/UMI4Cats