Commit c864b4f2 authored by harm's avatar harm
Browse files

Merge branch 'master' of gitlab.com:sanjanalab/cas13

parents 4951ddd5 cb8ae453
......@@ -31,7 +31,9 @@ This may increase the runtime of the first run by several minutes. We recommend
If older R versions are used, the Bioconductor package Biostrings may need to be installed manually via BiocLite.
Model input data as well as an example input fasta file are included within the data sub-sirectory.
Here we support installation on unix.
For MacOS installations, please compile the ViennaRNA package (https://www.tbi.univie.ac.at/RNA/) and replace the unix binaries in the path/to/Cas13design/scripts/ directory.
Windows is currently not supported.
Next, please install RNAhybrid.
......
......@@ -16,11 +16,16 @@ Hans-Hermann Wessels\*, Alejandro Méndez-Mancilla\*, Xinyi Guo, Mateusz Legut,
To download and install the Cas13 guide RNA scoring software, please follow the instructions in Install.txt.
```
wget https://gitlab.com/sanjanalab/cas13/-/blob/master/Cas13designGuidePredictor/Cas13design.tar.gz
wget -O Cas13design.tar.gz https://gitlab.com/sanjanalab/cas13/-/raw/master/Cas13designGuidePredictor/Cas13design.tar.gz?inline=false
tar -xzf Cas13design.tar.gz
cd Cas13design
cat Install.txt
```
Here we support installation on unix.
For MacOS installations, please compile the ViennaRNA package (https://www.tbi.univie.ac.at/RNA/) and replace the unix binaries in the path/to/Cas13design/scripts/ directory.
Windows is currently not supported.
<br>
<br>
......@@ -108,7 +113,7 @@ To predict guide RNA scores for all SARS-CoV-2 genes, one can use a simple wrapp
```sh
# This will submit one job per fasta file in the directory ./data/
bash qsub_MakePredictions.sh ./data/
bash qsub_MakePredictions.sh data
```
......@@ -8,7 +8,7 @@ Hans-Hermann Wessels\*, Alejandro Méndez-Mancilla\*, Xinyi Guo, Mateusz Legut,
The archive **Cas13design.tar.gz** entails the software needed to predict Cas13d guide RNA efficiencies on custom target RNA sequences. The software can be downloaded separately and installed following the enclosed Readme.txt file.
```
wget https://gitlab.com/sanjanalab/cas13/-/blob/master/Cas13designGuidePredictor/Cas13design.tar.gz
wget -O Cas13design.tar.gz https://gitlab.com/sanjanalab/cas13/-/raw/master/Cas13designGuidePredictor/Cas13design.tar.gz?inline=false
tar -xzf Cas13design.tar.gz
```
......
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