The AWH friction metric scale

Summary

Currently, the AWH friction metric is too large by a factor of (kb T)^2, so the diffusion coefficient from gmx awh -fric is too small by the same factor, 6.22 at 300 K in kJ/mol.

Existing runs do not need redoing and the correction can be applied in post-processing by multiplying/dividing the diffusion/friction by (kb*T)^2.

Exact steps to reproduce

Run any AWH run with a pull dimension and compare 1/friction against D from the MSD of the same trajectory.

Measured on a Martini3 solute in water, D from the MSD of the same trajectory, D in 1e-4, k = 500:

T (K) D_MSD D_AWH (2026.1) ratio (k_BT)^2
285 25.3 4.66 5.44 5.62
300 30.9 5.13 6.03 6.22
350 49.7 6.06 8.21 8.47

D_AWH hardly moves with temperature while the MSD nearly doubles. I also ran a 4 force constant x 3 temperature grid, ratio/(kb*T)^2 = 1.02 +/- 0.10.

Possible fixes

Fix could just loop over forceFromNeighbor and scaling by beta in updateForceCorrelationGrid(), after the calcUmbrellaForceAndPotential() call and before addData().

Edited by Panu Pulliainen