It sound there is an issue with recent boost-python library, as the corresponding `.so` filename evolved between [boost 1.65](https://ubuntu.pkgs.org/18.04/ubuntu-universe-i386/libboost-python1.65-dev_1.65.1+dfsg-0ubuntu5_i386.deb.html) and [boost 1.67](https://debian.pkgs.org/10/debian-main-i386/libboost-python1.67-dev_1.67.0-13+deb10u1_i386.deb.html). On a Ubuntu `20.04`, I get `libboost_python38.so`, whilst it would have been something like `libboost_python-py38.so` in previous versions. I will propose a patch on the `setup.py` to modify this line, which seems to be the key: ``` boost_python = 'boost_python-py{}{}'.format(*sys.version_info[:2]) if "BOOSTPYTHON_LIBNAME" not in os.environ else os.environ["BOOSTPYTHON_LIBNAME"] ```